Lionel Messi does not know if he will return from his current knee injury in time to play for Barcelona in the Clasico at Real Madrid on Nov. 21, his brother Rodrigo has told Spanish radio.

Messi tore a ligament in his left knee early this past weekend.

"[Messi] is an excellent professional and knows what he has to do," Rodrigo Messi said. "Obviously there is pressure in all aspects, but he is just thinking about his recovery. Nothing else. He really does not know [when he will return]. Nobody knows yet. His body will recover in its own time. There is no rush. Obviously he wants to play as quickly as possible, but he will only play when he is ready."

Messi will miss several World Cup qualifiers for Argentina in addition to Barcelona's normal schedule.

Lionel Messi will miss seven to eight weeks with a knee injury suffered in Barcelona's match in La Liga against Las Palmas.

The incident happened inside the opening stages at the Camp Nou, when Messi cut inside from the right wing, and his left footed shot was blocked by visiting defender Pablo Bigas.

Messi tried to continue for a few minutes, but he then came off for Barcelona.

Messi may miss El Clasico against Real Madrid at the Bernabeu on Nov. 21.

"Tests carried out on Leo Messi have confirmed that the player has suffered a tear in the internal collateral ligament of his left knee," the statement said. "The time out will be approximately between seven and eight weeks."

Christian Benteke will be out two weeks with a hamstring strain he suffered against Norwich City.

Liverpool’s £32.5 million summer signing from Aston Villa was withdrawn at halftime during Sunday’s 1-1 draw with Norwich after reporting a tight hamstring.

Benteke, who was already ruled out of Wednesday’s Capital One Cup third round tie against Carlisle United, will miss a reunion with Villa at Anfield on Saturday plus the Europa League tie at home to FC Sion next Thursday.

Jordan Henderson will be out for two months after breaking a bone in his foot.

Henderson suffered the injury on his return to team training.

Liverpool’s captain has already missed four out of six matches this season with a persistent problem in his left heel.

Gareth Bale will be out several weeks with a calf injury.

A club statement read: "Following the tests carried out on Gareth Bale today in the Sanitas La Moraleja University Hospital, the player has been diagnosed with a soleus muscle injury in his left leg. His condition will be evaluated."

Bale has suffered four calf injuries in two seasons with Real Madrid.

Rafinha suffered a torn ACL in his right knee during Barcelona's Champions League match on Wednesday at Roma.

Rafinha was on the receiving end of a heavy challenge from Roma midfielder Radja Nainggolan.

Rafinha had been on the pitch for just two minutes as a substitute. 

Thiago, Rafinha's brother who plays for Bayern Munich, has also suffered a torn ACL.

Sergio Ramos suffered a dislocated shoulder in Real Madrid's Champions League match on Tuesday against Shakhtar.

Marca reports that the usual recovery time for the injury would be around two weeks, but Ramos is holding out hope that he will be available for the meeting with Athletic Bilbao on Wednesday next week.

Luke Shaw suffered a horrific double fracture of his right leg in Manchester United's Champions League loss at PSV Eindhoven on Tuesday.

Shaw will be out at least six months.

The injury was caused by a reckless tackle from Héctor Moreno in the 15th minute.

Shaw had nine minutes of treatment on the field and needed oxygen before being taken to the hospital.

Louis Van Gaal said: “He has a double leg fracture and is in hospital. He will be transferred tomorrow or maybe a day later and then operated on in Manchester. It is awful – a boy who comes to Manchester United at 18, has it very difficult and then plays fantastically and then this happens. When it was in the dressing room he had an oxygen mask on. He was crying.

“I am not a doctor but when you have a double fracture it is six months and he will not play in the group phase. I hope he can play again this season.”

Franck Ribery could soon return for the first time since March.

Ribery's rehab progress from an ankle injury has been slower than expected.

“It is now mid-September and I think that will be the case, that during 2015 he will be whirling again,” Karl-Heinz Rummenigge said.

“What was important is to have the right diagnosis and treatment. I am not that pessimistic and I think in the not too distant future he will come back. That of course does not mean this week or next week,” Rummenigge said. “But he will come back. I am fully convinced of that and that is the key thing.”

Sergio Aguero injured his knee in Manchester City's 1-0 win at Crystal Palace.

Aguero suffered the injury on a challenge from Scott Dann.

Kevin de Bruyne came on for Aguero, marking his City debut.

"Thanks everyone for your concern. I got a hard hit and it prevented me from playing more. It doesn't seem to be a serious injury though," wrote Aguero on Twitter.