Cristiano Ronaldo may miss Real Madrid's Champions League semifinal first leg match against Manchester City with his thigh injury.

Ronaldo has already been ruled out of their La Liga match on Saturday.

“Tomorrow [Ronaldo] will not play,” Real’s coach, Zinedine Zidane, said on Friday. “We did the scans and he has nothing serious but he cannot play. Then we will see day to day. Tomorrow he will stay at home. Then we will see about Tuesday.”

It will be the first league game of the season Ronaldo has missed.

Divock Origi is expected to miss four to six weeks with an ankle ligament injury.

Origi scored his 10th goal of the season in Wednesday's defeat of Everton.

Fears that Origi had suffered a broken ankle were allayed by Jürgen Klopp after the 4-0 win. However, following a scan on Thursday, Liverpool fear the striker has suffered ligament damage.

Cristiano Ronaldo has downplayed the severity of a muscle injury in his right leg.

Ronaldo was substituted and limped off with the field with the injury.

Ronaldo posted an Instagram photo on Thursday saying: “All good. Thanks for your support”.

“He got a fright but I don’t think it is anything serious,” Zinedine Zidane told AS. “I am calmer now than when I saw him leave the pitch. For a coach when you have a player like Cristiano sometimes it is necessary for him to not play a game or not finish a match.”

Robert Lewandowski was involved in a car accident four days before his team's Champions League quarterfinal second leg clash against Benfica on Wednesday.

Lewandowski started on the bench in that game, and only came on in the 84th minute in place of Thomas Mueller, but Bayern's sporting director Matthias Sammer insisted the Polish striker's car accident on Sunday, did not influence Guardiola's decision to give him a bench role.

"Accidents happen to a lot of people, but you only rarely see prominent footballers involved." Sammer told Sky. "He is doing alright. These kinds of things happen.

"It was a minor accident. These things happen, but it did not have any influence on [Pep] Guardiola's decision."

Jordan Henderson will likely miss six to eight weeks with a knee ligament injury.

Henderson will likely miss the rest of Liverpool's season and possibly also miss the Euros for England.

Encouragingly for Henderson, however, the scan showed the injury to his LCL is isolated. 

Henderson does not require surgery, only treatment and an intensive period of rehabilitation, but would not play again for his club this season with a six-week recovery.