Alvaro Morata is out up to six weeks with a hamstring injury.
Morata had scored six goals in seven Premier League matches for Chelsea. Morata suffered the injury 10 minutes before halftime of Chelsea's 1-0 loss to Manchester City on Saturday.
Antonio Conte suggested Morata’s withdrawal had been precautionary and an attempt to ensure he did not sustain a more serious complaint.
Michy Batshuayi, the other recognised senior striker on the books after Diego Costa’s departure for £57 million last week, has scored five goals this season.