Manchester United will play Club Brugge, while Arsenal will face Olympiakos in the Europa League round of 32.
"Man United are a new challenge for my boys. For them the Europa League will be very important, but we are going to play our own game," said Brugge manager Philippe Clement.
The first leg takes place on February 20th.
The full draw is below:
Wolves vs. Espanyol
Sporting Lisbon vs. Istanbul Basaksehir
Getafe vs. Ajax
Bayer Leverkusen vs. Porto
FC Copenhagen vs. Celtic
APOEL vs. FC Basel
Cluj vs. Sevilla
Olympiakos vs. Arsenal
AZ Alkmaar vs. LASK
Club Brugge vs. Manchester United
FC Ludogorets vs. Inter Milan
Eintracht Frankfurt vs. FC Salzburg
Shakhtar Donetsk vs. Benfica
Wolfsburg vs. Malmo
Roma vs. Gent
Rangers vs. Braga