Chelsea at Manchester City (Sunday, 11:00 AM EST): Every sane person in August was predicting the Premier League champ to come from one of these two clubs and a month later everyone both sane and insane is saying the winner will be either Chelsea or City. 

City played at Arsenal last weekend, followed by a trip to Munich to face Bayern in the Champions League, so hosting Chelsea on Sunday is about as difficult of an eight-day period as any club will face in the month of September. 

Diego Costa came off the bench late for Chelsea against Schalke, while Yaya Toure sat against Arsenal. José Mourinho and Manuel Pellegrini each know that taking three points in this match gives their club the pole position as they begin the grind of the fall EPL schedule. The stakes don't get much higher than this match despite having so much season still ahead of us.

Juventus at AC Milan (Saturday, 2:45 PM EST): Juve are the clear favorites to win Serie A again, but Milan could have a run similar to Liverpool last season since they're only fighting on one front after not qualifying for Europe. They also play with tremendous pace and without much of a back line, just as Liverpool did last season. After scoring twice last week against Parma, Jérémy Menez upped the ante ahead of this match by suggesting Milan can win Serie A this season.