Graziano Pellè has been removed from the Italian squad for refusing to shake manager Gianpiero Ventura’s hand after being substituted.

Pellè was taken off on the hour after an ineffective display in the World Cup qualifier against Spain.

Pellè has been sent back to his club in China, Shandong Luneng, and will therefore miss Sunday’s qualifier in Macedonia.

“Unfortunately, it’s happened again, I’ve messed things up,” the 31-year-old said on Instagram.

“It was unacceptable behaviour, firstly against the coach and also, towards my team mates, who have always shown me to have important values in this fantastic Italy group we belong to.

“Like any great mistake, I accept the consequences. And it is only right that I take responsibility. I must ask offer my apologies from my heart to everyone.”