Sami Khedira will miss two months after sustaining a thigh injury.
Khedira joined Juventus from Real Madrid this summer.
A statement on Juve's official website read: "Sami Khedira will be sidelined for approximately two months after medical examinations revealed a second-grade myotendinous tear of the rectus femoris muscle in his right thigh.
"The German midfielder sustained the injury during last Saturday's preseason friendly against Olympique Marseille at the Stade Velodrome."