Manchester City at Southampton (Sunday, 8:30 AM EST): City was all set to enter the weekend losing to a 10-man Bayern side until Sergio Agüero happened. Saints have started the season exceptionally well, but have largely been untested with a soft schedule and this is the beginning of a gauntlet as they face Arsenal, United, Everton and Chelsea before New Year's. Southampton has been able to transition out of Mauricio Pochettino's departure under Ronald Koeman on the strength of its defense. Agüero will test that even as they face a City side that is far from full strength.

Gladbach at Wolfsburg (Sunday, 9:30 AM EST): Second place meets third place in the Bundesliga as both sides are trying to regain their footing following an exceptionally strong start. Gladbach hasn't been quite the same since Christoph Kramer's own goal disaster against Dortmund, losing 3-1 against Frankfurt and drawing this week against Villarreal. Gladbach had only allowed five goals in the Bundesliga before that Kramer own goal. Wolfsburg is scoring two goals per game, which only trails Bayern. Kevin de Bruyne and Ricardo Rodriguez will be noteworthy to watch for Wolves.

Barcelona at Valencia (Sunday, 3:00 PM EST): Luis Suárez scored his first goal since joining Barça during the Champions League this week, though that was of course overshadowed by Lionel Messi's hat-trick. Things seem to be clicking going forward for Barça while they've also organized their defense ever since the Clásico a month ago in which they were outclassed by Real Madrid. Valencia has slowed down somewhat from their fast start, but they should get Paco Alcácar back in the lineup, which could give them enough firepower to keep up with Barcelona.