Gareth Bale will miss Real Madrid's Champions League match on Wednesday against Liverpool, as well as El Clásico against Barcelona on Saturday.
Bale has a buttock injury that he's not fully recovered from.
Carlo Ancelotti could revert to the 4-4-2 he has been using when Bale is out of the lineup.
James Rodriguez and Isco could fit into the same team, accompanying Toni Kroos and Luka Modric in midfield.